By Brent Wells, PhD
Did Lucasfilm Ltd. direct an explosion in cloning efforts at first rumors of the storyline for Episode II, Attack of the Clones? Or did scientist’s unstoppable desire to achieve the impossible instruct the fate of the Empire? We may never know. But the happy coincidence and a recently christened holiday have brought you science in pictures so don’t think about it too much and enjoy.
If I’ve managed to assemble this infographic even half as well as I imagine George Lucas can assemble a sandwich, you probably command a decent understanding of the history of cloning technology by now. Like the special effects technologies developed at Industrial Light and Magic (ILM), cloning has advanced from its humble, yet provocative beginnings, into something awe-inspiring and useful at once. Unlike ILM special effects, each subsequent step in the maturation of cloning tech brings something more impressive than before.
A new study published just last week in the journal Nature describes the creation of a human, diploid, embryonic stem cell population using SCNT from an adult with Type 1 Diabetes. This is huge for a number of reasons: 1) They were able to use tissue from an adult, which negates any ethical concerns surrounding use of embryonic or fetal tissue. 2) They created diploid cells that can be used in treating human disease. Similar embryonic stem cells were generated in 2011 but were triploid, which means they contained three sets of chromosomes instead of the normal two found in humans, making them non-compatible and therefore inviable for use in disease treatment. 3) The stem cells, cloned from an individual with Type 1 Diabetes, can give rise to the very cells lost due to Type 1 Diabetes, and since they are clones of the affected individual, his/her body will not reject treatment that introduces new cells into their body to replace those lost to the disease.
This advancement in cloning technology is a significant step forward in creating stem cell banks that can actually be used in the study and treatment of disease on a case-by-case basis and will extend well beyond Diabetes. It also furthers efforts in the growth of complete replacement organs for those in need of matching donors – after all, there’s no better match for you than you.
If you want to learn more about cloning, *waves hand in front of face, uses weird voice inflection* You want to learn more about cloning. You’re going to look into the following resources. I am not the droid you’ve been looking for.
Wikipedia, of course
The Basic Science Partnership at Harvard Medical School
The Animal Biotechnology Resource at UCDavis
The Genetic Science Learning Center at the University of Utah Health Sciences
Or just Google it…
May the 4th be with you.
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